Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

L1cam  L1 cell adhesion molecule   (Synonyms: CD171, L1, L1-NCAM, NCAM-L1)
Results	Reference
1*	J:266538 Backer S, Lokmane L, Landragin C, Deck M, Garel S, Bloch-Gallego E, Trio GEF mediates RhoA activation downstream of Slit2 and coordinates telencephalic wiring. Development. 2018 Oct 2;145(19):dev153692
1	J:40497 Blackshear PJ, Silver J, Nairn AC, Sulik KK, Squier MV, Stumpo DJ , Tuttle JS, Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Exp Neurol. 1997 May;145(1):46-61
1	J:244667 Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, Yoshida Y, Simons M, Chauvet S, Mann F, Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017 Feb 22;8:14508
1	J:32083 Burmeister M, Novak J, Liang MY, Basu S, Ploder L, Hawes NL, Vidgen D, Hoover F, Goldman D, Kalnins VI, Roderick TH, Taylor BA, Hankin MH, McInnes RR, Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation. Nat Genet. 1996 Apr;12(4):376-84
1	J:138244 Chatzopoulou E, Miguez A, Savvaki M, Levasseur G, Muzerelle A, Muriel MP, Goureau O, Watanabe K, Goutebroze L, Gaspar P, Zalc B, Karagogeos D, Thomas JL, Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J Neurosci. 2008 Jul 23;28(30):7624-36
1*	J:71338 Chung WW, Lagenaur CF, Yan YM, Lund JS, Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb. J Comp Neurol. 1991 Dec 8;314(2):290-305
1	J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26
1	J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36
1	J:43652 Deiner MS, Kennedy TE, Fazeli A, Serafini T, Tessier-Lavigne M , Sretavan DW, Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia. Neuron. 1997 Sep;19(3):575-89
1	J:171029 Demyanenko GP, Siesser PF, Wright AG, Brennaman LH, Bartsch U, Schachner M, Maness PF, L1 and CHL1 Cooperate in Thalamocortical Axon Targeting. Cereb Cortex. 2011 Feb;21(2):401-12
1*	J:73528 Denaxa M, Chan CH, Schachner M, Parnavelas JG, Karagogeos D, The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development. 2001 Nov;128(22):4635-44
1*	J:103453 Denaxa M, Kyriakopoulou K, Theodorakis K, Trichas G, Vidaki M, Takeda Y, Watanabe K, Karagogeos D, The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Dev Biol. 2005 Dec 1;288(1):87-99
1	J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45
1	J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50
1	J:89119 Jones L, Lopez-Bendito G, Gruss P, Stoykova A, Molnar Z, Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
1	J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317
1	J:221642 Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L, The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36
1	J:320531 Kucukerden M, Schuster UE, Rockle I, Alvarez-Bolado G, Schwabe K, Hildebrandt H, Compromised mammillary body connectivity and psychotic symptoms in mice with di- and mesencephalic ablation of ST8SIA2. Transl Psychiatry. 2022 Feb 3;12(1):51
1*	J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69
1	J:144312 Lopez-Bendito G, Cautinat A, Sanchez JA, Bielle F, Flames N, Garratt AN, Talmage DA, Role LW, Charnay P, Marin O, Garel S, Tangential neuronal migration controls axon guidance: a role for neuregulin-1 in thalamocortical axon navigation. Cell. 2006 Apr 7;125(1):127-42
1*	J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28
1	J:215515 Magnani D, Hasenpusch-Theil K, Theil T, Gli3 controls subplate formation and growth of cortical axons. Cereb Cortex. 2013 Nov;23(11):2542-51
1	J:183861 Marcos-Mondejar P, Peregrin S, Li JY, Carlsson L, Tole S, Lopez-Bendito G, The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors. J Neurosci. 2012 Mar 28;32(13):4372-85
1	J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82
1*	J:117268 Nagae S, Tanoue T, Takeichi M, Temporal and spatial expression profiles of the Fat3 protein, a giant cadherin molecule, during mouse development. Dev Dyn. 2007 Feb;236(2):534-43
1	J:290851 Quintana-Urzainqui I, Hernandez-Malmierca P, Clegg JM, Li Z, Kozic Z, Price DJ, The role of the diencephalon in the guidance of thalamocortical axons in mice. Development. 2020 Jun 26;147(12):dev184523
1	J:206566 Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Dravis C, Kwan KY, Sestan N, Greenberg ME, Henkemeyer M, Cowan CW, EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2188-93
1	J:272212 Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Greenberg ME, Henkemeyer M, Cowan CW, EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure. Dev Neurobiol. 2016 Apr;76(4):405-20
1	J:308787 Samata B, Takaichi R, Ishii Y, Fukushima K, Nakagawa H, Ono Y, Takahashi J, L1CAM Is a Marker for Enriching Corticospinal Motor Neurons in the Developing Brain. Front Cell Neurosci. 2020;14:31
1	J:168547 Schiff M, Rockle I, Burkhardt H, Weinhold B, Hildebrandt H, Thalamocortical pathfinding defects precede degeneration of the reticular thalamic nucleus in polysialic Acid-deficient mice. J Neurosci. 2011 Jan 26;31(4):1302-12
1	J:163753 Sessa A, Mao CA, Colasante G, Nini A, Klein WH, Broccoli V, Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Genes Dev. 2010 Aug 15;24(16):1816-26
1	J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232
1	J:290119 Soleilhavoup C, Travaglio M, Patrick K, Garcao P, Boobalan E, Adolfs Y, Spriggs RV, Moles-Garcia E, Dhiraj D, Oosterveen T, Ferri SL, Abel T, Brodkin ES, Pasterkamp RJ, Brooks BP, Panman L, Nolz1 expression is required in dopaminergic axon guidance and striatal innervation. Nat Commun. 2020 Jun 19;11(1):3111
1*	J:335515 Tsuchimochi R, Yamagami K, Kubo N, Amimoto N, Raudzus F, Samata B, Kikuchi T, Doi D, Yoshimoto K, Mihara A, Takahashi J, Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain. Stem Cell Reports. 2023 Apr 11;18(4):899-914
1*	J:111612 Uemura M, Takeichi M, alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
1	J:64211 Vitalis T, Cases O, Engelkamp D, Verney C, Price DJ, Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J Neurosci. 2000 Sep 1;20(17):6501-16
1	J:297399 Vuong HE, Pronovost GN, Williams DW, Coley EJL, Siegler EL, Qiu A, Kazantsev M, Wilson CJ, Rendon T, Hsiao EY, The maternal microbiome modulates fetal neurodevelopment in mice. Nature. 2020 Oct;586(7828):281-286